MAN Vaporize 90 Softgels
The Highlights
* Radically reduces bodyfat through a process called fat oxidation
* Prevents the storage of fat by inhibiting lipogenic (fat storing) gene expression of several different fat storing enzymes
* Provides powerful anti-oxidant properties
* Positively stimulates cholesterol levels
* Supports healthy liver and kidney function
* Increases insulin sensitivity and acts as a nutrient partitioner
* Promotes anti-inflammatory effects
Sesamin
Sesamin is a lignan (a lignan is a chemical compound known as a phytoestrogen) and activates the Peroxisome Proliferator-Activator Receptor Alpha (PPAR alpha). There are 3 different classes of PPAR's:
1. Alpha - expressed in kidney, heart, muscle, adipose tissue, and others.
2. Gamma - though transcribed by the same gene, this PPAR exists in three forms (y-1 (expressed in virtually all tissues), y-2 (expressed primarily in fat tissue), y-3 (expressed in macrophages, intestines and white adipose tissue).
3. Delta - expressed in many tissues but markedly in brain, adipose tissue and skin.
PPAR's are nuclear receptors that play major roles in fat metabolism, cellular energy balance and insulin sensitivity. Basically they are small complexes that have major impact on many systems in our body and many systems that contribute to fat loss and nutrient usage/expenditure/storage. The PPAR alpha receptors can be found expressed in the muscle, liver, and kidneys, and is specifically involved in the transcription of the genes involved in the beta-oxidation (burning) of fatty acids and lipogenesis (the storing of fat). As such, sesamin does two significant things in regards to weight control/fat loss.
It produces the phenomenon known as fat oxidation by augmenting the release of potent thermogenic enzymes through optimized liver function. Meaning it helps increase the rate at which fat gets converted to energy. It prevents the storage of fat by inhibiting the function of fat storing enzymes. Sesamin can alter metabolism to be one that preferentially utilizes fat as an energy source as well as foil its storage. Supplemental to stopping the storage of body fat, sesamin's positive effects on cholesterol and reduced lipid synthesis do something else that might be even more important in reference to obesity by helping to maintain insulin sensitivity.
Another thing of importance to the war on obesity is that PPAR alpha activation (of which sesamin is extremely potent) also increases uncoupling-proteins (UCPs). What this means is that an increase in UCPs would increase the calories needed to produce the same amount of energy. In other words sesamin increases the rate and capacity at which cells can vaporize fat. One more thing to be noted is that sesamin is a powerful anti-inflammatory.
High-Lignan Flax Seed Oil
Flaxseed oil contains superior amounts of essential fatty acids, Omega-3, 6 which are known to have numerous health benefits. Among the proven health promoting properties of flaxseed oil are; cardiovascular health, healthy blood cholesterol, support healthy joints and bodyfat reduction. Flaxseed also contain lignans that have proven valuable in maintaining normal estrogen levels. As a rich source of omega-3 fatty acids and lignans, flaxseed oil can work in tandem with sesamin in activation of PPAR alpha and as such amplify the fat burning and health promoting properties of sesamin.
Supplement Facts:
Serving Size: 1 Softgel
Servings Per Container: 90
Amount Per Serving:
SesaThin Sesame Seed Oil SE: 500mg
(minimum 50% Sesamin)
Sesamin Lignan 250mg
High Lignan Flaxseed Oil 500mg
Alpha-Linolenic Acid (Omega-3 FA) 225mg
Linoleic Acid (Omega-6 FA) 55mg
Oleic Acid (Omega-9 FA) 55mg
Other Ingredients:
Gelatin, soybean oil, lecithin, water, glycerine.
Directions For Use:
Take one softgel 3 times daily with meals. Taking two softgels 3 times daily may provide greater benefit to those who tend to store body fat more easily.
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