NOW® Bromelain 2400 GDU is one of the highest natural potencies of this proteolytic (protein-digesting) enzyme available. While most enzymes are generally considered to be poorly absorbed, Bromelain is one of the most bioavailable of all enzymes and has been the subject of numerous studies worldwide.* Although Bromelain is derived from pineapples, supplementation is necessary to achieve optimum levels of this enzyme. Encapsulated in Vcaps® for a 100% vegetarian formula.

Your Bromelain tablets are labeled as having a potency of 2000 gdu/gram, yet I see that the Bromelain in Item 2996, Plant Enzyme Complex, is labeled as FCC (PU) units. What is the difference and is there a conversion between the two?

Bromelain can be standardized on Milk Clot Units (MCU/mg), Casein Digestion Units (CDU/mg), Bromelain Tyrosine Units (BTU/ gram), Rorer units, and more.

One FCC Papain Unit (PU), for example, is defined in this assay as that quantity of enzyme that liberates the equivalent of 1 µg (microgram) of tyrosine per hour under the conditions of the assay. This procedure is also used to determine the proteolytic activity of ficin and bromelain. The assay is based on a 60-min proteolytic hydrolysis of a casein substrate at pH 6.0 and 40° C. Soluble casein is then measured spectrophotometrically at 280nm.

Different activity-measuring methods can use different protein substrates as well as methods. Since enzymes are specific to peptide bonds and whicht terminal end of an amino acid it will cleave, there typically will not be a conversion between measures unless both measures are performed. This is why conversion among different enzyme measures can be so difficult.

In the case of the single ingredient formula, Bromelain at 2000 GDU/g would be equal to a 30,000,000 FCC PU/g potency.

Amount Per Servings:

Bromelain (2400 GDU) 500 mg

Other Ingredients:

Cellulose (capsule), Rice Flour and Magnesium Stearate (vegetable source). Vegetarian Formula.

Free of: sugar, salt, yeast, wheat, gluten, corn, soy, milk, egg or preservatives.

Directions For Use:

As a dietary supplement, take 1 Vcap® with or between meals.